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Graham Little-Piccardi-Lassueur syndrome

1 associated gene
7 signs/symptoms

PROTEIN INTERACTIONS: 1

Bullous pemphigoid

2 associated genes
12 signs/symptoms

Graham Little-Piccardi-Lassueur syndrome

Bullous pemphigoid

HLA-DRA	(UniProt - OMIM)		HLA-DQB1	(UniProt - OMIM)
			HLA-DRB1	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	HLA-DRA	(0.88)	HLA-DRB1

Citations in the biomedical literature:

Graham Little-Piccardi-Lassueur syndrome		Bullous pemphigoid
	Synonym(s): - Graham Little syndrome - Piccardi-Lassueur-Little syndrome		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare genetic disease - Rare skin disease		Classification (Orphanet): - Rare skin disease

	Classification (ICD10): - Diseases of the skin and subcutaneous tissue -		Classification (ICD10): - Diseases of the skin and subcutaneous tissue -

	Epidemiological data: (no data available)		Epidemiological data: (no data available)

	External references: No OMIM references No MeSH references		External references: No OMIM references 1 MeSH reference: D010391

Graham Little-Piccardi-Lassueur syndrome		Bullous pemphigoid
	Very frequent - Alopecia - Decreased body hair / axillar / pubic hairlessness - Follicular / erythematous / edematous papules / milium - Hyperkeratosis / ainhum / hyperkeratotic skin fissures - Hypotrichosis / atrichia / atrichiasis / scalp hairlessness Frequent - Lichen - Pruritus / itching		Very frequent - Autoimmunity / autoimmune reaction / autoantibodies - Diabetes mellitus - Eczema - Enanthema / aphtosa / aphta / leukoplakia - Erythema / erythematous lesions / erythroderma / polymorphous erythema - Immunodeficiency / increased susceptibility to infections / recurrent infections - Macules - Negative Nikolski's sign - Urticaria - Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment - Weight loss / loss of appetite / break in weight curve / general health alteration Frequent - Psoriasis